KPTI insider buying and SEC filings, explained
Karyopharm Therapeutics Inc. · CIK 1503802
Tracked: Forms 3/4/5, 8-K, NT · All filings on sec.gov
Company profile
- Exchanges
- Nasdaq
- Industry (SIC)
- Pharmaceutical Preparations
- State of incorporation
- DE
- Fiscal year end
- Dec 31
Insider activity in the last 12 months
Bought
$0
Insiders who bought
0
Sold (not marked 10b5-1)
$351K
Planned sales (10b5-1)
$0
Insider purchases and sales, last 12 months
| Traded | Type | What was filed | Source |
|---|---|---|---|
| Oct 16, 2026 | Sale | Kristin Abate (Chief Accounting Officer) sold 4,788 shares at $0.3440 ($2K). Holdings down 20% to 18,616 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed Oct 19, 2026, 4:03 PM ET |
| Oct 1, 2026 | Sale | Kristin Abate (Chief Accounting Officer) sold 378 shares at $1.19 ($450). Holdings down 2% to 23,404 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed Oct 2, 2026, 4:01 PM ET |
| Sep 1, 2026 | Sale | Kristin Abate (Chief Accounting Officer) sold 19 shares at $2.02 ($38). Holdings down <1% to 23,782 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed Sep 2, 2026 |
| Jul 28, 2026 | Sale | Stuart Poulton (EVP, Chief Development Officer) sold 189 shares at $7.10 ($1K). Holdings down <1% to 94,632 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed Jul 30, 2026 |
| May 14, 2026 | Sale | Stuart Poulton (EVP, Chief Development Officer) sold 403 shares at $9.50 ($4K). Holdings down <1% to 94,821 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed May 15, 2026 |
| May 14, 2026 | Sale | Reshma Rangwala (EVP & Chief Medical Officer) sold 408 shares at $9.50 ($4K). Holdings down 1% to 56,829 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed May 15, 2026 |
| May 14, 2026 | Sale | Sohanya Roshan Cheng (EVP & Chief Commercial Officer) sold 324 shares at $9.50 ($3K). Holdings down <1% to 107,940 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed May 15, 2026 |
| May 14, 2026 | Sale | Kristin Abate (Chief Accounting Officer) sold 53 shares at $9.50 ($504). Holdings down <1% to 23,801 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed May 15, 2026 |
| May 14, 2026 | Sale | Richard A. Paulson (CEO and Director) sold 2,203 shares at $9.50 ($21K). Holdings down 1% to 269,747 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed May 15, 2026 |
| May 14, 2026 | Sale | Michael Mano (EVP, CLO&Secretary) sold 266 shares at $9.50 ($3K). Holdings down <1% to 94,398 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed May 15, 2026 |
| Apr 21, 2026 | Sale | Reshma Rangwala (EVP & Chief Medical Officer) sold 449 shares at $8.94 ($4K). Holdings down 1% to 56,290 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed Apr 22, 2026 |
| Mar 2, 2026 | Sale | Kristin Abate (Chief Accounting Officer) sold 559 shares at $9.41 ($5K). Holdings down 2% to 22,063 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed Mar 3, 2026 |
| Mar 2, 2026 | Sale | Stuart Poulton (EVP, Chief Development Officer) sold 5,101 shares at $9.41 ($48K). Holdings down 5% to 94,328 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed Mar 3, 2026 |
| Mar 2, 2026 | Sale | Sohanya Roshan Cheng (EVP & Chief Commercial Officer) sold 4,604 shares at $9.41 ($43K). Holdings down 4% to 107,317 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed Mar 3, 2026 |
| Mar 2, 2026 | Sale | Michael Mano (EVP, CLO&Secretary) sold 3,526 shares at $9.41 ($33K). Holdings down 4% to 93,964 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed Mar 3, 2026 |
| Mar 2, 2026 | Sale | Reshma Rangwala (EVP & Chief Medical Officer) sold 5,066 shares at $9.41 ($48K). Holdings down 8% to 56,739 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed Mar 3, 2026 |
| Mar 2, 2026 | Sale | Richard A. Paulson (CEO and Director) sold 12,361 shares at $9.41 ($116K). Holdings down 4% to 267,030 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed Mar 3, 2026 |
| Feb 17, 2026 | Sale | Stuart Poulton (EVP, Chief Development Officer) sold 378 shares at $8.63 ($3K). Holdings down <1% to 99,429 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed Feb 19, 2026 |
| Feb 3, 2026 | Sale | Lori Macomber (CFO) sold 1,626 shares at $6.30 ($10K). Holdings down 2% to 85,105 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed Feb 4, 2026 |
| Jan 28, 2026 | Sale | Kristin Abate (Chief Accounting Officer) sold 50 shares at $7.03 ($352). Holdings down <1% to 22,622 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed Jan 29, 2026 |
| Jan 21, 2026 | Sale | Kristin Abate (Chief Accounting Officer) sold 265 shares at $5.96 ($2K). Holdings down 1% to 22,580 shares. Not marked as a 10b5-1 plan trade. | SEC filing Filed Jan 22, 2026 |
19 routine transactions (such as grants, option exercises or tax withholding) are not listed.
Cluster buys
No cluster buys in the last 12 months.
Red flags
| Tag | Items | Filed | Source |
|---|---|---|---|
| Red flag: debt acceleration | 8-K Item 2.04 | Nov 2, 2026, 9:58 PM ET | SEC filing |
| Red flag: bankruptcy or receivership | 8-K Item 1.03 | Nov 2, 2026, 9:58 PM ET | SEC filing |
Key events
No key events in the last 12 months.
8-K filings, last 12 months
| Filed | Items | Tag | Source |
|---|---|---|---|
| Nov 2, 2026, 9:58 PM ET 8-K | Material agreement (Item 1.01) Bankruptcy or receivership (Item 1.03) New debt or obligation (Item 2.03) Debt acceleration triggered (Item 2.04) Reg FD disclosure (Item 7.01) Other event (Item 8.01) | Red flag: debt acceleration Red flag: bankruptcy or receivership | SEC filing |
| Nov 2, 2026, 9:21 AM ET 8-K | Reg FD disclosure (Item 7.01) | SEC filing |
Red flags are objective triggers only: the item or form filed, never an opinion.
Follow KPTI in the Insider Ledger app
Get the appA plain-English brief of insider purchases, 8-Ks and red flags at the companies you pick. No account needed.